Ikonerne i verdenen er nøgle NPC'er hvorom magt og indflydelse drejer. Når det så er sagt, findes der stadig guder som folk tilbeder og som giver præster deres kræfter.
| Lawful Good gods | Domains |
|---|---|
| Bahamut, dragon god of good | Life, War |
| Heironeous, god of valor | War, Protection |
| Moradin, dwarf god of creation | Knowledge, Forge |
| Neutral Good gods | Domains |
| Fharlanghn, god of travel | Knowledge, Trickery |
| Garl Glittergold, gnome god of trickery and wiles | Trickery |
| Pelor, god of sun and healing | Life, Light |
| Chaotic Good gods | Domains |
| Corellon Larethian, elf god of art and magic | Light, Arcane |
| Ehlonna, goddess of woodlands | Life, Nature |
| Kord, god of athletics and sports | Tempest, War |
| Lawful Neutral gods | Domains |
| Pholtus, god of law | Light, Forge |
| St. Cuthbert, god of order and zeal | Knowledge, Protection |
| Neutral gods | Domains |
| Boccob, god of magic | Arcane, Knowledge |
| Celestian, god of stars | Knowledge |
| Istus, goddess of fate | Knowledge |
| Chaotic Neutral gods | Domains |
| Olidammara, god of revelry | Trickery |
| Obad-Hai, god of Nature | Nature, Tempest |
| Lawful Evil gods | Domains |
| Tiamat, dragon goddess of evil | Trickery, War |
| Hextor, god of war and discard | War |
| Wee Jas, goddess of magic and death | Death, Knowledge |
| Neutral Evil gods | Domains |
| Nerull, god of death | Death, Grave |
| Vecna, god of secrets | Knowledge, Trickery |
| Lolth, drow goddess of spiders | Trickery, Grave |
| Chaotic Evil gods | Domains |
| Gruumsh, orc god of storm and war | Tempest, War |
| Erythnul, god of envy and slaughter | War |
| Tharizdun, god of eternal darkness | Trickery, War |